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PRMEPRME

$3.32

-0.23
arrow_drop_down6.48%
Current Market·update13 Nov 2025 18:58
Day's Range
3.2735-3.56
52-week Range
1.11-6.94

Chart

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Performance

Key Stats

Next Earnings Date2025-11-07
Next Earnings TimeBefore Market Open
Volume2.4M
Average Volume 30d3.66M

AI PRME Summary

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-2
Valuation (P/E Ratio)
Negative P/E indicates losses. High P/S ratio suggests high valuation relative to revenue.
📈
-0.2415
EPS Growth (YoY)
Negative EPS and significant year-over-year decline.
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AI Scoreboard

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Overall Analysis

Buy
72

Prime Medicine Inc. demonstrates strong potential in the gene editing therapeutic space, supported by a solid balance sheet and promising technological advancements. However, it is still in an early growth phase with no revenue and significant cash burn, and its current stock price reflects high growth expectations.

Very Strong

Thematic

85

Prime Medicine is at the forefront of gene editing therapies, a rapidly expanding and transformative field. The company's proprietary Prime Editing technology offers a unique advantage in addressing a broad range of genetic diseases.

Strong

Fundamental

78

Prime Medicine possesses a strong balance sheet with substantial cash reserves, providing ample runway for its R&D efforts. However, the company is pre-revenue and exhibits significant operating losses, typical for its stage of development.

Neutral

Technical

45

The stock has experienced significant volatility. While it has seen upward momentum in the past month, it is currently trading below its 50-day and 200-day moving averages, suggesting a lack of sustained positive trend.

FactorScore
Gene Editing Technology Advancement95
Untapped Market Potential90
Biotechnology Innovation80
Competitive Landscape75
Regulatory Approval Pathway70
FactorScore
Valuation40
Profitability10
Growth0
Balance Sheet Health90
Cash Flow20
Debt Level85
FactorScore
Trend Analysis30
Momentum60
Volume Confirmation70
Support & Resistance50
Recent Performance70

AI Investing Checklist

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Bullish Points (7)

Performance chevron_right

Positive Recent Performance

The stock has shown strong recent performance, with a 1-month return of 74.59% and a Year-to-Date (YTD) return of 41.30%. This indicates significant positive momentum.

Financial Health & Liquidity chevron_right

Sufficient Cash Reserves

The company has substantial cash and cash equivalents (e.g., $182.48M in Q4 2024, $41.57M in Q4 2023, $187.62M in Q4 2022), which can support operations, R&D, and buffer against unforeseen challenges.

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Bearish Points (8)

Valuation chevron_right

High Price-to-Sales Ratio

The Price-to-Sales (PS) ratio is extremely high (e.g., 147.9x TTM, 184.1x for Q1 2025), indicating that the current market valuation is not supported by current sales revenue, suggesting high expectations for future growth.

Profitability chevron_right

Significant Net Losses

The company is experiencing substantial net losses (e.g., -$195.88M in 2024, -$198.13M in 2023) and negative EPS (-$1.61 TTM), indicating it is not yet profitable.

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Calendar

August 2025

7

Next Earnings Date

EPS Est.
Revenue Est.

H: $-0.26

A: $-0.34

L: $-0.42

H: 15.00M

A: 3.00M

0

Profile

Employees (FY)214
ISINUS74168J1016
FIGI-

Prime Medicine, Inc., a biotechnology company, engages in delivering genetic therapies to address the spectrum of diseases by deploying gene editing technology in the United States. It offers Prime Editing technology comprising a programmable DNA binding domains, such as Cas domains, are typically modified such that they do not cause a double-stranded break in the DNA, as well as a RT domain that copies the edited DNA sequence directly into the target genomic site where the edit is made; and pegRNA which contains a search sequence, also known as a spacer, which provides a target genomic address for the Prime Editor. The company has a research collaboration with Cimeio Therapeutics to develop Prime Edited Shielded-Cell & Immunotherapy Pairs for genetic diseases, acute myeloid leukemia, and myelodysplastic syndrome. Prime Medicine, Inc. was incorporated in 2019 and is headquartered in Cambridge, Massachusetts.

Seasonals

2025
2024
2023
2022

Price Target

7.36 USD

The 39 analysts offering 1 year price forecasts for PRME have a max estimate of 12.00 and a min estimate of 1.50.

Debt Level and Coverage

Debt
Free cash flow
Cash & equivalents

Financial Position Analysis

Assets
Liabilities

Ownership

Free Float shares
61.3M (45.59%)
Closely held shares
73.2M (54.41%)
134M
Free Float shares
61.3M (45.59%)
Closely held shares
73.2M (54.41%)

Capital Structure

Market cap
568.82M
Debt
40.79M
Minority interest
0.00
Cash & equivalents
182.48M
Enterprise value
427.14M

Valuation - Summary

Market Cap
569M
Net income
-147M(-25.79%)
Revenue
3.85M(0.68%)
569M
Market Cap
569M
Net income
-147M(-25.79%)
Revenue
3.85M(0.68%)
Price to earning ratio (P/E)-3.90x
Price to sales ratio (P/S)147.90x

Valuation - Ratios

P/E
P/S

Revenue to Profit Conversion

Revenue
2.98M
COGS
2.98M
Gross Profit
0.00
OpEx
205.45M
Operating Income
-202.47M
Other & Taxes
-6.58M
Net Income
-195.88M

Balance Sheet

Total assets
Total liabilities
Liabilities to assets %

Cash Flow

Operating Cash Flow
Investing Cash Flow
Financing Cash Flow
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