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IRDIRD

$4.16

+0.57
arrow_drop_up15.88%
Market closed·update27 Feb 2026 21:00

$4.1483

-0.01
arrow_drop_down0.28%
Post-market·update28 Feb 2026 00:41
Day's Range
3.529-4.165
52-week Range
0.65-4.17

Chart

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Performance

Key Stats

Next Earnings Date
Next Earnings TimeUnknown
Volume1.23M
Average Volume 30d791.45K

AI IRD Summary

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-1.4
Valuation (P/E Ratio)
Negative P/E, indicative of losses. Not comparable to traditional P/E benchmarks.
📈
-3.28
EPS Growth (YoY)
Significant decline in earnings (last 5 days). YoY data not directly available for EPS growth, but YTD performance is -6.35%.
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AI Scoreboard

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Overall Analysis

Hold
57

Opus Genetics (IRD) is a clinical-stage biopharmaceutical company focused on inherited retinal diseases. While its thematic potential in addressing unmet medical needs is significant, current financial performance, valuation, and technical indicators suggest a neutral to cautious outlook. The company operates in a high-risk, high-reward sector, and further clinical trial success and revenue generation are critical for long-term value realization.

Moderate

Thematic

70

Opus Genetics operates within the rapidly advancing field of gene therapy for rare diseases, specifically inherited retinal diseases (IRDs). The unmet medical need in this area is substantial, and successful development of its pipeline therapies could lead to significant market penetration. However, the inherent risks in clinical-stage biopharmaceutical development, including trial failures and regulatory hurdles, temper the thematic score.

Weak

Fundamental

35

Opus Genetics is a clinical-stage biopharmaceutical company with no revenue generation from product sales. Its financial health is characterized by significant net losses and negative earnings per share, typical for its stage. The company relies on financing activities to fund its operations. While it holds substantial cash reserves, continued cash burn necessitates future fundraising, which carries dilution risk.

Neutral

Technical

45

The stock price of Opus Genetics (IRD) has experienced significant volatility, reflecting its development stage and market sentiment. Current technical indicators suggest a neutral to slightly bearish short-term outlook. The price is trading below key moving averages, and oscillators are mixed, indicating a lack of strong directional conviction.

FactorScore
Ophthalmic Gene Therapy Market80
Pipeline Development Stage60
Competition Landscape65
Regulatory Environment for Gene Therapy75
Partnerships and Collaborations50
FactorScore
Valuation30
Profitability5
Growth0
Balance Sheet Health60
Cash Flow10
Earnings Per Share (EPS)5
FactorScore
Trend Analysis30
Momentum40
Volume Confirmation50
Support & Resistance50
Moving Averages (Longer Term)30

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Bullish Points (6)

Earnings Performance chevron_right

Positive Earnings Surprises

The company has exceeded earnings per share (EPS) estimates in the last two reported quarters (2025 Q1 and 2025 Q2), indicating improving operational efficiency and profitability.

Financial Health & Liquidity chevron_right

Strong Cash Position

As of Q1 2025, the company holds $41.8 million in cash and cash equivalents, providing a significant buffer and flexibility for future investments and operations.

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Bearish Points (8)

Profitability & Margins chevron_right

Consistent Net Losses

The company has reported significant net losses in the trailing twelve months (TTM) and annual periods (2023, 2024), with a negative net margin indicating unprofitability.

Earnings Performance chevron_right

Negative Earnings Per Share (EPS)

EPS (TTM) is reported at -2.1, and quarterly EPS estimates and reported figures are consistently negative, highlighting a lack of profitability on a per-share basis.

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Calendar

November 2020

6

Next Dividend Date

August 2025

11

Next Earnings Date

EPS Est.
Revenue Est.

H: $-0.26

A: $-0.26

L: $-0.26

H: 4.50M

A: 4.27M

L: 4.00M

Profile

Employees (FY)18.0
ISIN-
FIGI-

Opus Genetics, Inc., a clinical-stage ophthalmic biopharmaceutical company, focuses on developing and commercializing therapies for the treatment of inherited retinal diseases (IRDs). It develops OPGx-LCA5, an early-onset retinal degeneration that is in Phase 1/2 clinical trial for the treatment of LCA5-associated IRD; and OPGx-BEST1 to treat BEST1-associated retinal disease. The company also develops various pre-clinical IRD programs, including OPGx-RHO, a gene therapy that targets autosomal dominant retinitis pigmentosa caused by RHO mutations; OPGx-RDH12 that is designed to restore protein expression and halt functional deterioration in patients with retinal dystrophy caused by mutations in the retinal dehydrogenase gene; OPGx-MERTK, an AAV vector for the treatment of MERTK IRD; OPGx-NMNAT1, a gene augmentation therapy designed to halt functional deterioration in pediatric patients with retinal degenerative disease caused by mutations in the nicotinamide mononucleotide adenylyltransferase 1 gene; and OPGx-CNGB1, an AAV gene therapy for retinitis pigmentosa due to mutations in the CNGB1 gene. In addition, it develops Phentolamine Ophthalmic Solution for reversal of mydriasis, as well as for the treatment of presbyopia and dim light or night vision disturbances; and APX3330, a small-molecule inhibitor of Ref-1 for the treatment of diabetic retinopathy. The company was formerly known as Ocuphire Pharma, Inc. Opus Genetics, Inc. was founded in 2018 and is headquartered in Durham, North Carolina.

Seasonals

2025
2024
2023
2022
2021

Price Target

6.00 USD

The 39 analysts offering 1 year price forecasts for IRD have a max estimate of 8.00 and a min estimate of 5.00.

Debt Level and Coverage

Debt
Free cash flow
Cash & equivalents

Financial Position Analysis

Assets
Liabilities

Ownership

Free Float shares
49.7M (83.37%)
Closely held shares
9.92M (16.63%)
59.7M
Free Float shares
49.7M (83.37%)
Closely held shares
9.92M (16.63%)

Capital Structure

Market cap
70.4M
Debt
538K
Minority interest
0.00
Cash & equivalents
24.53M
Enterprise value
46.4M

Valuation - Summary

Market Cap
70.4M
Net income
-50.9M(-72.24%)
Revenue
12.5M(17.81%)
70.4M
Market Cap
70.4M
Net income
-50.9M(-72.24%)
Revenue
12.5M(17.81%)
Price to earning ratio (P/E)-1.40x
Price to sales ratio (P/S)5.60x

Valuation - Ratios

P/E
P/S

Revenue to Profit Conversion

Revenue
10.99M
COGS
10.99M
Gross Profit
0.00
OpEx
45.07M
Operating Income
-34.07M
Other & Taxes
23.46M
Net Income
-57.53M

Balance Sheet

Total assets
Total liabilities
Liabilities to assets %

Income Statement

Revenue
Net Income
Net Margin

Cash Flow

Operating Cash Flow
Investing Cash Flow
Financing Cash Flow