COYACoya Therapeutics shows potential in the biotechnology sector, with early-stage clinical progress and a focus on neurodegenerative diseases. However, the company is pre-revenue, highly speculative, and faces significant clinical and regulatory risks. Its current financial position and lack of profitability indicate a high-risk, high-reward profile. Investors should consider the early stage of development and the inherent volatility of clinical-stage biotechs.
Coya Therapeutics is positioned within the biotechnology sector, with specific focus on neurodegenerative diseases like ALS, Frontotemporal Dementia, Alzheimer's, and Parkinson's. The growing prevalence of these conditions and advancements in cellular therapies present a significant thematic tailwind.
As a clinical-stage company, Coya Therapeutics has no current revenue or profits. Its financial health is characterized by significant operating expenses and a reliance on external financing. The company's valuation metrics are not applicable in the traditional sense due to the absence of earnings.
The stock has experienced significant volatility, with a recent upward trend but still trading below its 52-week high. Technical indicators suggest mixed signals, with some positive momentum but also potential resistance levels and caution warranted due to low volume.
| Factor | Score |
|---|---|
| Biotechnology Innovation | 80 |
| Neurodegenerative Disease Market | 85 |
| Cell and Gene Therapy Trends | 70 |
| Regulatory Environment (Biotech) | 65 |
| Collaboration & Partnerships | 75 |
| Factor | Score |
|---|---|
| Valuation | 10 |
| Profitability | 5 |
| Growth | 30 |
| Balance Sheet Health | 50 |
| Cash Flow | 20 |
| Factor | Score |
|---|---|
| Trend Analysis | 50 |
| Momentum | 55 |
| Volume Confirmation | 40 |
| Support & Resistance | 65 |
Strong Short-Term Performance
The stock has shown positive performance across multiple short-term periods, with 5D (+17.22%), 1M (+14.02%), and YTD (+16.81%) returns indicating recent upward momentum.
Low Beta
A Beta of 0.26 suggests lower volatility relative to the overall market, which can be attractive for risk-averse investors.
Negative EPS
The Earnings Per Share (EPS) for the trailing twelve months (TTM) is -$1.07, and recent quarterly EPS estimates are negative, indicating ongoing losses.
High Price-to-Sales Ratio
The Price-to-Sales (PS) ratio is extremely high, with TTM at 429.3 and 2025Q1 at 419.6, suggesting the company's current market valuation is not supported by its current sales and could be a significant risk.
Coya Therapeutics, Inc., a clinical-stage biotechnology company, develops proprietary therapies to enhance the function of regulatory T cells (Tregs). The company's product candidate pipeline is based on therapeutic modalities, such as Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy. It develops COYA 302, a biologic combination for subcutaneous administration intended to enhance Treg function while depleting T effector function and activated macrophages in Phase 2 trial for use in the treatment of amyotrophic lateral sclerosis, as well as frontotemporal dementia, Alzheimer's disease (AD), and Parkinson's disease. In addition, the company's pre-clinical product candidates include COYA 301, a low-dose interleukin 2 product candidate to treat AD; COYA 303, an investigational biologic combination of COYA 301 and a glucagon-like-peptide-1 receptor agonist for the treatment of inflammatory diseases; COYA 201, an antigen directed Treg-derived exosome product candidate to treat neurodegenerative, autoimmune, and metabolic diseases; COYA 206, an antigen directed Treg-derived exosome product candidate; and COYA 101. It has a collaboration with Dr. Reddy's Laboratories SA for the development and commercialization of COYA 302, an investigational combination therapy for treatment of amyotrophic lateral sclerosis. Coya Therapeutics, Inc. was founded in 2020 and is headquartered in Houston, Texas.
16.64 USD
The 39 analysts offering 1 year price forecasts for COYA have a max estimate of 20.00 and a min estimate of 14.00.