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ZYMEZYME

$23.29

-0.52
arrow_drop_down2.18%
Market closed·update27 Feb 2026 21:00
Day's Range
22.94-23.66
52-week Range
9.03-28.49

Chart

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Performance

Key Stats

Next Earnings Date2026-03-02
Next Earnings TimeBefore Market Open
Volume437.96K
Average Volume 30d704.59K

AI ZYME Summary

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-13.8
Valuation (P/E Ratio)
Currently has negative P/E due to losses; compare with Price-to-Sales (P/S) of 14.1.
📈
0.54
Revenue Growth (YoY)
Significant revenue increase from 2023 to 2024.
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AI Scoreboard

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Overall Analysis

Buy
75

Zymeworks shows strong fundamental and thematic potential, particularly in its innovative biotherapeutics pipeline. However, recent financial performance indicates a need for careful monitoring, and technical indicators suggest a mixed short-term outlook.

Very Strong

Thematic

85

Zymeworks is positioned in the high-growth biotechnology sector, focusing on cancer and autoimmune diseases, with promising therapeutic platforms and a lead drug candidate in late-stage trials.

Neutral

Fundamental

65

While revenue has shown some growth, the company is experiencing significant net losses. The balance sheet appears healthy with ample cash, but the lack of profitability and consistent negative free cash flow requires attention.

Bullish

Technical

70

The stock has experienced significant upward momentum in the short term, trading above key moving averages. However, some oscillators indicate it might be approaching overbought conditions.

FactorScore
Biotechnology Innovation95
Therapeutic Focus90
Drug Development Technology80
Strategic Partnerships75
Market Adoption Potential85
FactorScore
Valuation40
Profitability10
Growth30
Balance Sheet Health70
Cash Flow20
FactorScore
Trend Analysis90
Momentum60
Volume Confirmation65
Support & Resistance70
Short-term Oscillators75

AI Investing Checklist

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Bullish Points (9)

Market Performance chevron_right

Positive Short-Term Performance

The stock has shown a significant increase of 16.67% in the last month, indicating positive short-term momentum.

Market Performance chevron_right

Strong Year-to-Date Performance

The stock has experienced a 48.88% increase over the last year, demonstrating strong long-term performance.

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Bearish Points (10)

Earnings Performance chevron_right

Negative Earnings Per Share (EPS)

The company has consistently reported negative EPS in recent quarters, with EPS estimates for 2025 also being negative, indicating ongoing unprofitability.

Earnings Performance chevron_right

Significant Negative Surprise in EPS

Q1 2025 EPS estimate was -0.1, but reported EPS was -0.31, a surprise of -213.13%, indicating a substantial miss on earnings expectations.

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Calendar

August 2025

8

Next Earnings Date

EPS Est.
Revenue Est.

H: $-0.32

A: $-0.46

L: $-0.58

H: 27.00M

A: 17.18M

L: 10.00M

Profile

Employees (FY)299
ISINUS98985Y1082
FIGI-

Zymeworks Inc., a clinical-stage biotechnology company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer, and autoimmune and inflammatory diseases (AIID). Its therapeutic platforms and fully integrated drug development engine provides the flexibility and compatibility to precisely engineer and develop highly differentiated antibody-based therapeutic candidates. The company's platforms include Azymetric multispecific antibody platform; Drug Conjugate platform includes a suite of proprietary cytotoxins comprising topoisomerase and microtubulin inhibiting toxins, stable linkers, and conjugation technologies; EFECT platform, which consists of a set of modifications to the Fc region of antibodies that enable the selective modulation of recruited cytotoxic immune cells for various therapeutic applications; and ProTECT, a tumor-specific immune co-stimulation platform. Its lead product candidate consists of zanidatamab, a novel bispecific antibody that targets human epidermal growth factor receptor 2 HER2 that is in Phase 1, Phase 2, and Phase 3 clinical trials, including certain ongoing pivotal clinical trials; and zanidatamab zovodotin, a HER2 -targeted antibody-drug conjugate that is in Phase 2 clinical trial for the treatment of advanced or metastatic HER2-expressing tumors. In addition, the company develops a pipeline of preclinical product candidates. It has strategic partnerships and collaborations with BeiGene, Ltd.; Celgene Corporation; Celgene Alpine Investment Co. LLC; GlaxoSmithKline Intellectual Property Development Limited; Daiichi Sankyo Co., Ltd.; Iconic Therapeutics, Inc.; Merck Sharp & Dohme Research GmbH; and Atreca, Inc. Zymeworks Inc. was incorporated in 2003 and is based in Middletown, Delaware.

Seasonals

2025
2024
2023
2022
2021

Price Target

21.56 USD

The 39 analysts offering 1 year price forecasts for ZYME have a max estimate of 30.00 and a min estimate of 12.00.

Debt Level and Coverage

Debt
Free cash flow
Cash & equivalents

Financial Position Analysis

Assets
Liabilities

Ownership

Free Float shares
35.7M (47.64%)
Closely held shares
39.2M (52.36%)
74.8M
Free Float shares
35.7M (47.64%)
Closely held shares
39.2M (52.36%)

Capital Structure

Market cap
1.05B
Debt
18.51M
Minority interest
0.00
Cash & equivalents
66.1M
Enterprise value
1B

Valuation - Summary

Market Cap
1.05B
Net income
-76M(-7.25%)
Revenue
74.1M(7.07%)
1.05B
Market Cap
1.05B
Net income
-76M(-7.25%)
Revenue
74.1M(7.07%)
Price to earning ratio (P/E)-13.80x
Price to sales ratio (P/S)14.10x

Valuation - Ratios

P/E
P/S

Revenue to Profit Conversion

Revenue
76.3M
COGS
76.3M
Gross Profit
0.00
OpEx
196.12M
Operating Income
-119.82M
Other & Taxes
2.88M
Net Income
-122.69M

Balance Sheet

Total assets
Total liabilities
Liabilities to assets %

Income Statement

Revenue
Net Income
Net Margin

Cash Flow

Operating Cash Flow
Investing Cash Flow
Financing Cash Flow
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