RNACCartesian Therapeutics (RNAC) is a clinical-stage biotechnology company focused on mRNA cell therapies for autoimmune diseases. The company exhibits potential driven by its lead candidate, Descartes-08, but faces significant risks associated with clinical trial progression, binary outcomes, and substantial cash burn. Its current fundamental and technical outlook presents a mixed picture, warranting a 'Hold' rating.
The company operates within the growing biotechnology sector, with a specific focus on mRNA technology and autoimmune disease treatments. While these areas have strong long-term tailwinds, the specific application and stage of development for RNAC's therapies are critical factors.
RNAC's financials show a company with substantial cash reserves for its stage, but also significant operating losses and negative free cash flow. The P/E ratio is not applicable due to negative earnings, and the Price-to-Sales ratio is high, reflecting its early-stage valuation. The company has no dividend yield.
RNAC's stock price has experienced significant volatility. While short-term momentum indicators show mixed signals, longer-term trends and key moving averages suggest potential upward momentum, though recent performance indicates weakness. The stock has recently seen considerable price swings.
| Factor | Score |
|---|---|
| Biotechnology Sector Growth | 75 |
| Autoimmune Disease Market | 70 |
| Clinical Stage Risk | 40 |
| Regulatory Landscape (Biotech) | 60 |
| Factor | Score |
|---|---|
| Valuation | 30 |
| Profitability | 10 |
| Growth | 50 |
| Balance Sheet Health | 80 |
| Cash Flow | 20 |
| Debt Level | 85 |
| Factor | Score |
|---|---|
| Trend Analysis | 50 |
| Momentum | 45 |
| Moving Averages | 60 |
| Volume | 40 |
| Short-Term Performance | 70 |
| Long-Term Performance | 30 |
Recent Positive Momentum
The stock price has seen positive performance over multiple short-term periods, with a 5-day performance of +8.62% and a 1-month performance of +23.88%.
Low Price-to-Earnings Ratio
The trailing P/E ratio (PE_TTM) of 2.48 is exceptionally low, suggesting the stock may be significantly undervalued based on its current earnings.
Significant Long-Term Decline
Despite recent short-term gains, the stock has experienced a significant decline over longer periods, with a 6-month performance of -31.87% and a 1-year performance of -22.99%.
Negative Earnings and High Price-to-Sales
The company has consistently reported negative net income (e.g., -$77.42 million in 2024, -$219.71 million in 2023) and a very high Price-to-Sales ratio (PS) of 471.7 (TTM), indicating a lack of profitability and a speculative valuation.
August 2025
14
Next Earnings Date
H: $-0.65
A: $-0.65
L: $-0.65
H: 5.00M
A: 812.50K
0Cartesian Therapeutics, Inc., a clinical-stage biotechnology company, provides mRNA cell therapies for the treatment of autoimmune diseases. The company's lead product candidate is Descartes-08, an autologous mRNA CAR-T directed against the B cell maturation antigen (BCMA), which is in Phase 2b clinical trials for the treatment of autoimmune diseases, generalized myasthenia gravis, and systemic lupus erythematosus, as well as rare pediatric disease designation for the treatment of juvenile dermatomyositis. It is also developing Descartes-15, an autologous anti-BCMA mRNA CAR-T to treat autoimmune diseases, such as relapsed/refractory multiple myeloma. The company is headquartered in Frederick, Maryland.
36.43 USD
The 39 analysts offering 1 year price forecasts for RNAC have a max estimate of 42.00 and a min estimate of 16.00.