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CYTKCYTK

$65.94

-0.56
arrow_drop_down0.84%
Current Market·update12 Nov 2025 21:00
Day's Range
65.07-66.98
52-week Range
29.31-66.98

Chart

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Performance

Key Stats

Next Earnings Date2025-11-05
Next Earnings TimeAfter Market Close
Volume2.38M
Average Volume 30d2.3M

AI CYTK Summary

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-9.4
Valuation (P/E Ratio)
Negative P/E ratio, common for biotech in development phase
📈
-0.15
EPS Growth (YoY)
Negative EPS growth, typical for companies investing heavily in R&D
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AI Scoreboard

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Overall Analysis

Neutral
68

Cytokinetics shows potential in its core therapeutic areas but faces significant financial challenges and mixed technical signals. Investors should monitor clinical trial progress and financing activities.

Moderate

Thematic

75

The company operates within the growing biopharmaceutical sector, focusing on cardiovascular diseases which have significant unmet needs. Success in clinical trials and market adoption of its therapies are key thematic drivers.

Weak

Fundamental

65

Cytokinetics faces considerable financial headwinds, characterized by significant losses, negative earnings, and substantial debt. While revenues are growing, they are not yet sufficient to offset high operating expenses and R&D costs.

Neutral

Technical

70

The stock's short-term technicals are mixed. While it shows some recent upward momentum, it is trading below key moving averages, and oscillators suggest a neutral to slightly bearish short-term outlook.

FactorScore
Biotechnology & Pharmaceuticals Growth80
Cardiovascular Disease Market85
Drug Development & Clinical Trials70
Competition Landscape60
Partnerships and Collaborations70
FactorScore
Valuation15
Profitability5
Growth75
Balance Sheet Health30
Cash Flow10
Earnings Per Share (EPS)5
FactorScore
Trend Analysis40
Momentum50
Volume Confirmation60
Support & Resistance70
Short-Term Performance65

AI Investing Checklist

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Bullish Points (5)

Company Profile & Business Model chevron_right

Focus on Late-Stage Biopharmaceutical Development

Cytokinetics is a late-stage biopharmaceutical company focused on discovering, developing, and commercializing treatments for debilitating diseases. Its focus on muscle activators and inhibitors targets significant unmet medical needs in areas like heart failure and hypertrophic cardiomyopathy. The company has a pipeline of drug candidates in various clinical trial phases (Phase I, II, and III), indicating a commitment to innovation and product development. Strategic alliances and collaborations, such as with Ji Xing Pharmaceuticals Limited, can accelerate development and expand market reach.

Financial Performance & Growth chevron_right

Revenue Growth and Emerging Market Potential

While recent quarterly revenue figures are low, the company's focus on commercialization of its pipeline drugs, such as aficamten (in Phase III for hypertrophic cardiomyopathy), suggests significant future revenue potential. The collaboration for aficamten in Japan indicates an expansion strategy into key international markets. Investors should monitor the progress of clinical trials and regulatory approvals as key drivers for future revenue and profitability.

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Bearish Points (5)

Financial Performance & Profitability chevron_right

Persistent Net Losses and Negative Margins

Cytokinetics has consistently reported significant net losses, with a net income of -$589.53 million in Q4 2024. The net margin remains deeply negative, reflecting the high costs associated with drug development without substantial commercial revenue. Gross profit is also negative (-$320.93 million in Q4 2024), indicating that current revenues do not cover the cost of goods sold or associated R&D expenses, a typical characteristic of pre-revenue biopharma companies.

Valuation chevron_right

High Price-to-Sales Ratio

The company's trailing Price-to-Sales (P/S) ratio is very high, indicated by values like 304.1 (2024) and 591.7 (2023). This reflects the current limited revenue base relative to its market capitalization. The P/E ratio is also not applicable due to persistent losses. These valuation metrics highlight the speculative nature of investing in the company at this stage, as future success hinges on the successful commercialization of its pipeline.

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Calendar

August 2025

8

Next Earnings Date

EPS Est.
Revenue Est.

H: $-0.35

A: $-1.35

L: $-1.60

H: 15.00M

A: 1.95M

0

Profile

Employees (FY)498
ISIN-
FIGI-

Cytokinetics, Incorporated, a late-stage biopharmaceutical company, focuses on discovering, developing, and commercializing muscle activators and inhibitors as potential treatments for debilitating diseases in the United States. The company develops small molecule drug candidates primarily engineered to impact muscle function and contractility. Its drug candidates include omecamtiv mecarbil, a novel cardiac myosin activator that is in Phase III clinical trial in patients with heart failure. It also develops CK- 089, a fast skeletal muscle troponin activator that is in Phase I clinical trial; CK-586, a small molecule cardiac myosin inhibitor, that is in Phase II clinical trial; and aficamten, a novel, oral, small molecule cardiac myosin inhibitor which is in Phase III clinical trial discovered for the treatment of hypertrophic cardiomyopathy. It has a strategic alliance with Ji Xing Pharmaceuticals Limited; and a collaboration and license agreement for the development and commercialization of aficamten in Japan for the treatment of patients with obstructive and non-obstructive hypertrophic cardiomyopathy. Cytokinetics, Incorporated was incorporated in 1997 and is headquartered in South San Francisco, California.

Seasonals

2025
2024
2023
2022
2021

Price Target

72.55 USD

The 39 analysts offering 1 year price forecasts for CYTK have a max estimate of 120.00 and a min estimate of 41.00.

Debt Level and Coverage

Debt
Free cash flow
Cash & equivalents

Financial Position Analysis

Assets
Liabilities

Ownership

Free Float shares
119M (99.52%)
Closely held shares
579K (0.48%)
119M
Free Float shares
119M (99.52%)
Closely held shares
579K (0.48%)

Capital Structure

Market cap
4.46B
Debt
788.68M
Minority interest
0.00
Cash & equivalents
94.86M
Enterprise value
5.15B

Valuation - Summary

Market Cap
4.46B
Net income
-472M(-10.59%)
Revenue
19M(0.43%)
4.46B
Market Cap
4.46B
Net income
-472M(-10.59%)
Revenue
19M(0.43%)
Price to earning ratio (P/E)-9.40x
Price to sales ratio (P/S)234.90x

Valuation - Ratios

P/E
P/S

Revenue to Profit Conversion

Revenue
18.47M
COGS
339.41M
Gross Profit
-320.93M
OpEx
215.31M
Operating Income
-536.25M
Other & Taxes
53.28M
Net Income
-589.53M

Balance Sheet

Total assets
Total liabilities
Liabilities to assets %

Income Statement

Revenue
Net Income
Net Margin

Cash Flow

Operating Cash Flow
Investing Cash Flow
Financing Cash Flow
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